There are four layouts to choose from. Decide what you want your page too look like and what kinds of things you want to put on your page and choose the layout you want to use. When you have decided on the layout you want to use click on it. You will be taken back to your editing page where you can see the new look of your page.
Some layouts won't work with some looks. Try one, if you don't like the way it looks you can always change it later.